9-1-1: Nashville’ star Isabelle Tate’s untimely death at 23 from a rare Charcot-Marie-Tooth disease has left Hollywood in mourning.

Actress Isabelle Tate, best known for her appearance in the 9-1-1: Nashville series premiere, has tragically passed away at just 23 years old.
Her family and talent agency confirmed that she died on October 19, with the cause of death later revealed to be a rare form of Charcot-Marie-Tooth disease (CMT) — a progressive neurological disorder that affects the nerves controlling movement and sensation.
Born and raised in Tennessee, Isabelle Tate was seen as a rising star in the entertainment industry. Her agency, The McCray Agency, shared the heartbreaking news on Instagram, writing, “We are deeply saddened and completely heartbroken to share that Isabelle Tate passed away on October 19th.” The statement added that she “died peacefully” and that her family is asking for privacy as they navigate this unimaginable loss.
In 2022, Tate had opened up about her condition on Instagram, revealing that she had been living with a progressive neuromuscular disease since she was 13. “Over the years, I was going on with my life and would notice little things get more difficult for me,” she wrote, explaining how the disease gradually weakened her leg muscles.
Charcot-Marie-Tooth disease is a genetic neurological disorder that damages the peripheral nerves, which connect the brain and spinal cord to the muscles and sensory organs.
According to the Mayo Clinic, these nerves are responsible for transmitting signals that control muscle movement and relay sensations such as touch or temperature.
While the disease typically progresses slowly, severe forms can interfere with muscles that control breathing and swallowing, potentially leading to life-threatening complications.
The condition is named after the three doctors who first identified it in 1886: Jean-Martin Charcot and Pierre Marie in France, and Howard Henry Tooth in England.
Despite being one of the most common inherited nerve disorders, there is currently no cure for CMT. Treatments mainly focus on symptom management—through physical therapy, custom footwear, leg braces, medications, or surgery.
Following Tate’s passing, her agency encouraged donations to the Charcot-Marie-Tooth Association, which funds research for new treatments and supports patients living with the disease.
Tate’s story has also brought renewed attention to the condition—one that has affected others in the entertainment world, including country music legend Alan Jackson, who revealed his own diagnosis in 2021.
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Fans are remembering Isabelle Tate not only for her talent but for her bravery. Her final role on 9-1-1: Nashville may have marked the beginning of a promising career, but her story leaves behind something far greater — a legacy of strength, honesty, and hope for others facing the same battle.
